Atorvastatin is used with diet changes (restriction of cholesterol and fat intake) to reduce the amount of cholesterol and certain fatty substances in your blood.

The following Information is intended to supplement, not to substitute the expertise and judgment of your pharmacist, physician or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you.

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Atorvastatin is used with diet changes (restriction of cholesterol and fat intake) to reduce the amount of cholesterol and certain fatty substances in your blood. Accumulation of cholesterol and fats along the walls of your arteries (a process known as atherosclerosis) decreases blood flow and, therefore, the oxygen supply to your heart, brain, and other parts of your body. Lowering your blood level of cholesterol and fats may help to prevent heart disease, angina (chest pain), strokes, and heart attacks.

What is Atorvastatin?
Atorvastatin is a prescription drug in one of the newest classes of cholesterol-lowering medications, called statins. These drugs have been used widely for the last five years. For people with high cholesterol, Atorvastatin, in combination with a low-fat diet, can reduce your LDL cholesterol and triglyceride levels.

How does Atorvastatin work?
Atorvastatin works by blocking an enzyme in the liver that your body uses to make cholesterol. When less cholesterol is produced, the liver takes up more cholesterol from the bloodstream. This results in lower levels of cholesterol circulating in your blood.

How does Atorvastatin improve the different types of cholesterol?
In medical studies of people with high cholesterol, Atorvastatin, taken once a day, had the following effects at doses of 10 to 80 mg: Lowered total cholesterol by 29-45%. Lowered LDL cholesterol, the "bad" cholesterol, by 39-60%. Increased HDL cholesterol, the "good" cholesterol, by 5-9%. Lowered triglyceride levels by 19-37%.

What are the effects of Atorvastatin tablets?
Atorvastatin is a very effective medicine for lowering high LDL cholesterol—the main target of cholesterol-lowering therapy. Your doctor will determine how much your LDL cholesterol needs to be lowered, based on your overall risk of heart disease. Atorvastatin also effectively lowers high blood-triglyceride levels.

What would I need to know about taking Atorvastatin?
Most people will require the starting dose, which is a 10 mg tablet once daily. Your doctor will prescribe the dose that is right for you, which may be 10 mg to 80 mg. Atorvastatin can be taken any time of the day, with or without food. To make it easier to remember to take Atorvastatin you can plan to take it at the same time each day, such as after you brush your teeth in the evening. The amount or how often Atorvastatin is taken should never be changed without consulting your healthcare professional.

How long does it take Atorvastatin to work?
Generally, Atorvastatin works within 2 weeks. The full effect is usually seen within 4 weeks and lasts as long as you continue taking it. Always take Atorvastatin as directed by your healthcare professional.

Who should not take Atorvastatin tablets?
Some people should not take Atorvastatin. Those with active liver disease or possible liver problems; women who are pregnant, could possibly become pregnant, or are breast-feeding; and people who are allergic to any of the ingredients in LIPITOR.

Atorvastatin is generally well tolerated and side effects are usually mild. In studies, the most common side effects associated with Atorvastatin were constipation, flatulence, indigestion, and abdominal pain. If you are prescribed Atorvastatin, your healthcare professional may want to conduct routine blood tests to check your liver function before and after starting treatment. Be sure to tell your healthcare professional if you have any allergies to food or medication. Also, report promptly any unexplained muscle pain, tenderness, or weakness, particularly if accompanied by discomfort or fever, as these symptoms may be signs of serious side effects.

For information about taking Atorvastatin along with other medicines, see your doctor or pharmacist. If you experience side effects, be sure to tell your doctor or other healthcare professional.

If you take Atorvastatin with certain other medicines, they may affect one another. Atorvastatin may interact with certain other cholesterol-lowering drugs, some antibiotics, and antifungal medications. It may also interact with less-frequently prescribed medications as immunosuppressives (given after transplants). Be sure to tell your doctor or pharmacist about all prescription and nonprescription drugs you are taking.

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

Store at room temperature between 59 and 86 degrees F (15-30 degrees C) away from light and moisture. Keep this and all medicine out of the reach of children.